A N-phenylnaphthalimide derivative with aggregation-induced emission for cell imaging

HUANG Wenling; JIANG Na; ZHU Ying; HUANG Wanling; QU Yi

doi:10.12299/jsues.21-0237

Volume 36 Issue 3

Jun. 2022

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Article Navigation > Journal of Shanghai University of Engineering Science > 2022 > 36(3): 301-308

HUANG Wenling, JIANG Na, ZHU Ying, HUANG Wanling, QU Yi. A N-phenylnaphthalimide derivative with aggregation-induced emission for cell imaging[J]. Journal of Shanghai University of Engineering Science, 2022, 36(3): 301-308. doi: 10.12299/jsues.21-0237

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HUANG Wenling, JIANG Na, ZHU Ying, HUANG Wanling, QU Yi. A N-phenylnaphthalimide derivative with aggregation-induced emission for cell imaging[J]. Journal of Shanghai University of Engineering Science, 2022, 36(3): 301-308. doi: 10.12299/jsues.21-0237

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A N-phenylnaphthalimide derivative with aggregation-induced emission for cell imaging

doi: 10.12299/jsues.21-0237

School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China

Received Date: 2021-10-31
Publish Date: 2022-06-30

Abstract

Abstract

Aggregation-induced emission (AIE)-active materials show important applications in organic photoelectric functional materials. By introducing a phenyl ring, a deplanarization core into the 4-site of naphthalimide chromophore through the typical Suzuki coupling reaction, two new AIE molecules (NIRF2 and NIRF6) based on the common ACQ-active naphthalimide dye were designed and synthesized. Their structures were fine characterized by ¹H & ¹³C NMR and HRMS spectra. The structure-properties relationships were discussed by UV-vis and fluorescent spectra and dynamic laser scattering tests. Finally, both NIRF2 and NIRF6 were successfully applied to image the cytoplasm of the Hela cells. The study results show that the optimized designing strategy can achive the naphthalimide-based AIE-active molecules.
- naphthalimide,
- aggregation-induced emission (AIE),
- cell imaging

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References(17)

References

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