无机纳米催化剂在化学动力学疗法的研究进展

白鑫; 张旻昳; 郑喃喃; 王金霞; 赵行; 管少琪; 王星妍; 陆杰; 刘锡建

无机纳米催化剂在化学动力学疗法的研究进展

上海工程技术大学化学化工学院，上海 201620

详细信息

作者简介:
白鑫：白　鑫（1999−），男，在读本科生，研究方向为化学工程与工艺. E-mail：1395038345@qq.com

通讯作者:
刘锡建（1978−），男，副教授，博士，研究方向为生物材料. E-mail：liuxijian@sues.edu.cn

中图分类号: O 643.1
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- 文章访问数: 588
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- 被引次数: 0
出版历程
- 收稿日期: 2020-08-07
- 刊出日期: 2020-12-30

Research Progress of Inorganic Nano-Catalyst for Chemodynamic Therapy

School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China

摘要

摘要: 化学动力学疗法（CDT）是一种侵袭性小的新兴肿瘤治疗方式. 其通过将纳米催化剂引入肿瘤治疗中，促进肿瘤内产生特定毒性的活性氧，从而杀死肿瘤细胞. 从化学动力疗法的原理，无机纳米催化材料的选择，CDT协同光热治疗、化疗、光动力学治疗、放疗共同提升肿瘤治疗效率这几个方面进行综述，说明CDT有望成为一种新型的替代性的肿瘤治疗方式.
- 化学动力学疗法（CDT） /
- 纳米催化剂 /
- 协同治疗 /
- 芬顿反应
Abstract: Chemodynamic therapy (CDT) is a minimally aggressive emerging cancer treatment, which introduces nanocatalysts into cancer treatment to promote the production of specific toxic reactive oxygen species (ROS) in tumors, inducing the death of tumor cells. Summaried from the aspects of the mechanism of CDT, the choice of nanocatalytic materials, and combinations of CDT with photothermal therapy, chemotherapy, photodynamic therapy and radiotherapy to improve the efficiency of tumor treatment, it indicates that the CDT is expected to become an alternative method of tumor treatment.
- chemodynamic therapy（CDT） /
- nanocatalysts /
- synergistic treatment /
- Fenton reaction

HTML全文

图 1 HPFeS₂@C-TA-PEI-GOx-FA的制备工艺及治疗机理^[11]

Figure 1. Preparation process and therapeutic mechanism of HPFeS₂@C-TA-PEI-GOx-FA

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图 2 CDT和PTT协同治疗

Figure 2. Synergistic treatment of CDT and PTT

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图 3 CDT和化疗协同治疗

Figure 3. Synergistic treatment of CDT and chemotherapy

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图 4 CDT和PDT协同治疗

Figure 4. Synergistic treatment of CDT and PDT

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图 5 CDT和放疗协同治疗

Figure 5. Synergistic treatment of CDT and radiotherapy

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